Journal ArticleAuthors : Daffern, Nicolas (2023)
Transcriptional coactivators occupy an important niche in promoting gene transcription
in eukaryotes. They lack the sequence-specific DNA-binding activity that characterizes
transcriptional activators, but commonly serve two critical functions: (i) as molecular
adaptors bridging promoter- and enhancer-bound activators with the transcription
machinery and (ii) as agents that serve to overcome the repressive effects of chromatin [1,
2]. In the latter instance, ... 
