Journal articleAuthors : Dandekar, B. (2021)
Cytochrome P450, the ubiquitous metalloenzyme involved in detoxification of foreign components, has remained one of the
most popular systems for substrate-recognition process. However, despite being known for its high substrate specificity, the
mechanistic basis of substrate-binding by archetypal system cytochrome P450cam has remained at odds with the contrasting
reports of multiple diverse crystallographic structures of its substrate-free form. Here we address this...