Browsing by Author Jain, Neha

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  • OER000000842.pdf.jpg
  • Journal article


  • Authors : Jain, Neha; Tamborrini, Davide; Evans, Brian (2020)

  • Chromatin remodelling complexes are multi-subunit nucleosome translocases that reorganize chromatin in the context of DNA replication, repair and transcription. A key question is how these complexes find their target sites on chromatin. Here, we use genetically encoded photo-crosslinker amino acids to map the footprint of Sth1, the catalytic subunit of the RSC (remodels the structure of chromatin) complex, on the nucleosome in living yeast. We find that ...