Journal ArticleAuthors : Kagohashi, Yoko (2023)
Autophagy is a lysosomal/vacuolar delivery system that isolates and degrades cytoplasmic
material. Following delivery by autophagosomes, cytoplasmic components are released into the
vacuole within an autophagic body (AB), which is a single-membrane structure derived from the
inner membrane of the autophagosome. This membrane must be disrupted for degradation of the
cytoplasmic cargo to occur. The vacuolar proteases Pep4 and Prb1, as well as the&...