Journal articleAuthors : Farrell, Daniel P; Anishchenko, Ivan; Shakeel, Shabih (2020)
Cryo-electron microscopy of protein complexes often leads to moderate resolution maps (4-8 Å), with visible secondary structure elements but poorly resolved loops, making model-building challenging. In the absence of high-resolution structures of homologues, only coarse-grained structural features are typically inferred from these maps, and it is often impossible to assign specific regions of density to individual protein subunits. This paper describes a new method for... 
