Periodicals (Báo – Tạp chí)Authors : Lamy, Anaïs; Bruzaferro, Ewerton Macarini; Marín, Alex Perálvarez (2020)
Efficient mechanisms of lipid transport are indispensable for the Plasmodium malaria parasite along the different stages of its intracellular life-cycle. Gene targeting approaches have recently revealed the irreplaceable role of the Plasmodium-encoded type 4 P-type ATPases (P4-ATPases or lipid flippases), ATP2, together with its potential involvement as antimalarial drug target. In eukaryotic membranes, P4-ATPases assure their asymmetric phospholipid distribution by translocating pho...