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  • OER000002310.pdf.jpg
  • Journal Article


  • Authors : Mendes, Luis Felipe S.; Costa-Filho, Antonio J. (2023)

  • Eukaryotic cells evolved to possess efficient secretory machinery capable of transporting a significant fraction of their proteome. The number of proteins predicted to enter the secretory pathway can reach up to 36% of the total proteome in humans (1). Proteins entering the secretory pathway are efficiently sorted to a specific destination: the extracellular space, the plasma membrane, or the interior of the endomembrane system. The machinery also has&#x...