Digital resources - Ha Noi university of science and technology

Browsing by Author Aleshin, Vasily A.

Jump to: 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
or enter first few letters:

Showing results 1 to 1 of 1

Journal article

Protein-protein interfaces as druggable targets: A common motif of the pyridoxal-5’-phosphate-dependent enzymes to receive the coenzyme from its producers

Authors : Aleshin, Vasily A. (2023)

The enzymes using pyridoxal-5’-phosphate (PLP) as the coenzyme encompass more than 300 31 distinct catalytic functions, belonging to five of the seven existing EC classes [1]. Many of these 32 reactions, particularly those involving amino acid metabolism, are critical for not only metabolic 33 switches underlying malformations, but also the elimination of malignant cells. For instance, PLP- 34 dependent transaminases drive T cells activation and...