Browse

Author Profile

Browsing by Author Benador, Ilan Y

Jump to: 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
or enter first few letters:  
Showing results 1 to 1 of 1
  • OER000004056.pdf.jpg
  • Journal article

  • Blocking mitochondrial pyruvate import causes energy wasting via futile lipid cycling in brown fat

    • Authors : Veliova, Michaela; Ferreira, Caroline M; Benador, Ilan Y (2019)

  • Futile lipid cycling is an ATP-wasting process proposed to participate in energy expenditure of mature fat-storing white adipocytes, given their inability to oxidize fat. The hallmark of activated brown adipocytes is to increase fat oxidation by uncoupling respiration from ATP synthesis. Whether ATP-consuming lipid cycling can contribute to BAT energy expenditure has been largely unexplored. Here we find that pharmacological inhibition of the mitochondrial pyruvate...