Journal ArticleAuthors : Bryan, Nikaela W. (2023)
Membraneless intracellular compartmentalization is central to a long and growing list of
biochemical transactions at diverse sub-cellular locations 1. Proteins are by-and-large the
drivers of the formation of these compartments, but there is debate about whether their
underpinnings are either low-affinity/low-specificity interactions yielding phase separation 2 or
multivalent site-specific interactions 3. By its very nature, ascertaining the former type of
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