Journal ArticleAuthors : Buchanan, Jane L. (2023)
Tryptophan is an essential amino acid that is extensively characterized as a regulator of
cellular function through its metabolism by indoleamine 2,3-deoxygenase (IDO) into the
kynurenine pathway. However, despite decades of research on tryptophan metabolism, the
metabolic regulatory roles of it and its metabolites are not well understood. To address this, we
performed an activity metabolomics screen of tryptophan and most of its known metabolit... 
