Journal ArticleAuthors : Davies, Jonathan P. (2023)
Coronaviruses (CoV), including SARS-CoV-2, modulate host proteostasis through
activation of stress-responsive signaling pathways such as the Unfolded Protein Response
(UPR), which remedies misfolded protein accumulation by attenuating translation and
increasing protein folding capacity. While CoV nonstructural proteins (nsps) are essential for
infection, little is known about the role of nsps in modulating the UPR. We characterized the
impact of SARS-CoV-2 ns... 
