Browsing by Author Enam, Syed Usman

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  • Periodicals (Báo – Tạp chí)


  • Authors : Enam, Syed Usman; Zinshteyn, Boris; Goldman, Daniel H (2020)

  • Puromycin is a tyrosyl-tRNA mimic that blocks translation by labeling and releasing elongating polypeptide chains from translating ribosomes. Puromycin has been used in molecular biology research for decades as a translation inhibitor. The development of puromycin antibodies and derivatized puromycin analogs has enabled the quantification of active translation in bulk and single-cell assays. More recently, in vivo puromycylation assays have become popular tools for loc...