Journal ArticleAuthors : Hoare, Bradley L. (2023)
Measurements of membrane protein thermostability allows indirect detection of ligand
3 binding. Current thermostability assays require protein purification or rely on pre4
existing radiolabelled or fluorescent ligands, limiting their application to established
5 target proteins. Alternative methods detect protein aggregation which requires
6 sufficiently high level of protein expression.
7 Here, we present a ThermoBRET method to quantify the relative thermost... 
