Journal articleAuthors : Kømurcu, Kristina Sæterdal (2023)
Oxysterols are potential biomarkers for liver metabolism that are altered under disease
13 conditions such as non-alcoholic fatty liver disease (NAFLD). We here apply sterolomics to
14 organoids used for disease modeling of NAFLD. Using liquid chromatography-mass spectrometry
15 with on-line sample clean-up and enrichment, we establish that liver organoids produce and
16 secrete oxysterols. We find elevated levels of 26-hydroxycholesterol, an LXR ago... 
