Journal articleTác giả : Kumar, Arun HS (2021)
Recombinant neprilysin due to its degradation potential against Amyloid-β (Aβ)
peptides has been looked at as a potential therapeutic candidate for treating
Alzheimer’s disease (AD). However the enzymatic activity of neprilysin against
different Aβ peptides can variable which significantly limits the therapeutic
optimization. Using the molecular interaction analysis and modelling it against the
known enzyme-substrate kinetics, this study developed a novel...