Journal ArticleAuthors : Marien, Jules (2023)
The microtubule-associated protein (MAP) tau plays a key role in the regulation of
microtubule assembly and spatial organisation. Tau hyperphosphorylation affects its
binding on the tubulin surface and has been shown to be involved in several pathologies
such as Alzheimer disease. As the tau binding site on the microtubule lays close to the
disordered and highly flexible tubulin C-terminal tails (CTTs), these are likely to impact
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