Browsing by Author Movsik, Jonathan

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  • OER000000400.pdf.jpg
  • Journal article


  • Authors : Goldman, Daniel H; Livingston, Nathan M; Movsik, Jonathan (2020)

  • Translation of problematic mRNA sequences induces ribosome stalling. Collided ribosomes at the stall site are recognized by cellular quality control machinery, resulting in dissociation of the ribosome from the mRNA and subsequent degradation of the nascent polypeptide and in some organisms, decay of the mRNA. However, the timing and regulation of these processes are unclear. We developed a SunTag-based reporter to monitor translation in real time on sin...