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Browsing by Author Penner, Tiffany V.

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  • OER000002357.pdf.jpg
  • Journal Article

  • Structural characterization of the Sel1-like repeat protein LceB from Legionella pneumophila

    • Authors : Penner, Tiffany V. (2023)

  • Legionella are freshwater Gram-negative bacteria that in their normal environment infect protozoa. However, this adaptation also allows Legionella to infect human alveolar macrophages and cause pneumonia. Central to Legionella pathogenesis are more than 330 secreted effectors, of which there are 9 core effectors that are conserved in all pathogenic species. Despite their importance, the biochemical function of several core effectors remains unclear. ...