Journal ArticleAuthors : Prus, Gabriela (2023)
Ubiquitylation regulates virtually all proteins and biological processes in a cell. However, the
global site-specific occupancy (stoichiometry) and turnover rate of ubiquitylation have never
been quantified. Here, we present the first integrated picture of ubiquitylation site
occupancy and half-life. Ubiquitylation occupancy spans four orders of magnitude, but the
median ubiquitylation site occupancy is three orders of magnitude lower than that of
20... 
