Browsing by Author Serrano, Fidel E.

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  • Journal Article


  • Authors : Serrano, Fidel E. (2023)

  • Casein kinase 1δ (CK1δ) is a simple monomeric enzyme involved in the regulation of a variety of functions, including signal transduction, the circadian clock, and the cell cycle. Although CK1δ is targeted by the ubiquitin ligase APC/CCdh1 is not understood how CK1δ expression is regulated to support its multiple functions. Here, we show that kinase activity controls CK1δ homeostasis by coordinating two competing processes: export ...