Journal articleAuthors : Thillaivillalan, Dhanaraman; Singh, Swati; Killoran, Ryan C (2020)
Activated RAS GTPases signal by directly binding effector proteins. Effectors have a folded
RAS association (RA) domain that binds exclusively to GTP-loaded RAS, but the specificity of
most RA domains for >150 RAS superfamily GTPases is unknown. Ten RAS-association
domain family (RASSF) proteins comprise the largest group of effectors, proposed to couple
RAS to the pro-apoptotic Hippo pathway. We show that RASSF1-6 complex ... 
