Journal articleAuthors : Tsowa, Swen (2021)
Proteins interacting with ADP-ribosyl groups are often involved in disease-related pathways or in viral
infections, which makes them attractive targets for the development of inhibitors. Our goal was to
develop a robust and accessible assay technology that is suitable for high-throughput screening and
applicable to a wide range of proteins acting as either hydrolysing or non-hydrolysing binders of mono and poly-ADP-ribosyl groups. As a fou...