Tìm kiếm theo: Tác giả Weeks, Amy M

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  • OER000000858.pdf.jpg
  • Journal article


  • Tác giả : Weeks, Amy M; Byrnes, James R; Lui, Irene (2020)

  • N terminomics is a powerful strategy for profiling proteolytic neo-N termini, but its application to cell surface proteolysis has been limited by the low relative abundance of plasma membrane proteins. Here we apply plasma membrane-targeted subtiligase variants to efficiently and specifically capture cell surface N termini in live cells. Using this approach, we sequenced 807 cell surface N termini and quantified changes in their abundance in response to&...