Journal ArticleAuthors : wicks, sarah L. (2023)
The use of small molecules to modulate RNA structure and function has become invaluable for
studying the many roles of RNA in biological processes1 as well as discovering effective
therapeutic treatments.2-5 Early on, the promise of RNA as a ‘druggable’ target was demonstrated
by the identification of several RNA-targeting small molecule classes such as aminoglycosides.6,
7 These ligands bound highly abundant and structured ribosomal RNA (r...