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Journal article

G protein βγ subunits bind to and inhibit the function of multiple Qa- and Qb,c-SNARE isoforms

Authors : Zurawski, Zack (2023)

While the ability of G protein βγ subunits (Gβγ) to bind to and functionally inhibit the neuronal SNARE proteins Stx1A, SNAP25, and synaptobrevin in the presence of the calcium sensor synaptotagmin I is well documented, these three SNARE proteins, which form the core SNARE complex for synchronous evoked release in neurons, are but a subset of the larger family of SNARE proteins, which participate in many other exocytic proces...