Journal articleAuthors : Muckenfuss, Lena M. (2023)
3’ end formation of most eukaryotic mRNAs is dependent on the assembly of a ~1.5 megadalton
3 multiprotein complex, that catalyzes the coupled reaction of pre-mRNA cleavage and polyadenylation.
4 In mammals, the cleavage and polyadenylation specificity factor (CPSF) constitutes the core of the
5 3’ end processing machinery onto which the remaining factors, including cleavage stimulation factor
6 (CstF) and poly(A) polymerase (PAP), assemble.... 
