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Browsing by Subject Aquifex aeolicus RNase P

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  • OER000002957.pdf.jpg
  • Journal article

  • Structure and mechanistic features of the prokaryotic minimal RNase P

    • Authors : Feyh, Rebecca (2021)

  • Endonucleolytic removal of 5’-leader sequences from tRNA precursor transcripts (pre-tRNAs) by RNase P is essential for protein synthesis. Beyond RNA-based RNase P enzymes, protein-only versions of the enzyme exert this function in various Eukarya (there termed PRORPs) and in some bacteria (Aquifex aeolicus and close relatives); both enzyme types belong to distinct subgroups of the PIN domain metallonuclease superfamily. Homologs of Aquifex RNase P (HARPs) are ...