Journal articleTác giả : Schmitz, Michael (2023)
CRISPR systems have been co-opted by Tn7-like elements to direct RNA-guided transposition. Type
V-K CRISPR-associated transposons rely on the concerted activities of the pseudonuclease Cas12k,
the AAA+ ATPase TnsC, the Zn-finger protein TniQ, and the transposase TnsB. Here we present a
cryo-electron microscopic structure of a target DNA-bound Cas12k-transposon recruitment complex
comprising RNA-guided Cas12k, TniQ, TnsC and, unexpectedly, the ribosomal protein ... 
