Journal articleAuthors : Johanna, Hörberg (2023)
Transcription factors (TFs) regulate eukaryotic transcription through selecting DNA-binding,
can also specifically interact with RNA, which may present another layer of transcriptional
control. The mechanisms of the TFs-DNA recognition are often well-characterised, while the
details of TFs-RNA complexation are less understood. Here we investigate the dual
recognition mechanism of the glucocorticoid receptor (GR), which interacts with similar
affinities with consen...