Journal ArticleAuthors : Serwanja, Jamil (2023)
Collagens form the resilient backbone of the extracellular matrix in mammals. Only few proteases are able to digest triple-helical collagen. Clostridial collagenases can efficiently process collagen. However, little is known about the mechanism of bacterial collagenolyis of either soluble collagen or the multi-hierarchically assembled, insoluble collagen fibers. Here we present a functional analysis of the distinct roles of the individual domains of collagenase G (ColG... 
