Journal ArticleTác giả : Paweletz, Laura C. (2023)
The activity of membrane proteins depends strongly on the surrounding lipid environment.
Here, we characterize the lipid stimulation of the plant plasma membrane H+-ATPase AHA2
upon purification and reconstitution into liposomes of defined lipid compositions. We show that
the proton pumping activity of AHA2 is stimulated by anionic phospholipids, especially by
phosphatidylserine. Molecular dynamics simulations revealed several preferential contact sites
for...