Periodicals (Báo – Tạp chí)Tác giả : Liaci, A. Manuel (2020)
The signal peptidase complex (SPC) is an essential membrane complex in the endoplasmic reticulum (ER), here it removes signal peptides (SPs) from a large variety of secretory pre-proteins with exquisite specificity. Although the determinants of this process have been established empirically, the molecular details of SP recognition and removal remain elusive. Here, we show that the human SPC exists in two functional paralogs with distinct roteolytic subu... 
