Journal articleAuthors : Kikuchi, Masaki (2023)
Histone acetylation is important for the activation of gene transcription but little is known
14 about its direct ‘read/write’ mechanisms. Here, we report cryo-electron microscopy structures
15 in which a p300/CBP multidomain monomer recognizes histone H4 N-terminal tail (NT)
16 acetylation (ac) in a nucleosome and acetylates non-H4 histone NTs within the same
17 nucleosome. p300/CBP not only recognized H4NTac via the bromodomain pocke... 
