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  • OER000002287.pdf.jpg
  • Journal Article

  • Flexibility and distributive synthesis regulate RNA priming and handoff in human DNA polymerase α-primase

    • Authors : Cordoba, John J (2023)

  • In eukaryotes, DNA polymerase α-primase (pol-prim) initiates DNA synthesis during replication, generating the first ~30 nucleotides of nascent strands.1–5 Pol-prim is unique among replicative polymerases in its ability to perform de novo synthesis from a single-stranded DNA template; the primers it creates are required for further synthesis by the processive polymerases ε and δ that perform the bulk of nascent strand synthesis6,7. Pol-prim plays a particularly...
  • OER000002804.pdf.jpg
  • Journal article

  • Power system flexibility: A review

    • Authors : O. M, Babatunde, (2019)

  • Power systems networks are traditionally structured and engineered to effectively accommodate the effects of uncertainty and variability as regards energy demand and availability of resources. In order to transform the present carbon-intensive electricity generation system to one driven largely by clean energy sources, the inclusion of variable renewable energy sources (vRES) is becoming predominant. However, the inclusion of large vRES in the power plant mix incr...