Browse

Author Profile

Browsing by Subject Thụ thể hạt nhân

Jump to: 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
or enter first few letters:  
Showing results 1 to 2 of 2
  • OER000002330.pdf.jpg
  • Journal Article

  • Prostaglandins as Candidate Ligands for a Per-ARNT-Sim (PAS) Domain of Steroid Receptor Coactivator 1 (SRC1)

    • Authors : Daffern, Nicolas (2023)

  • Transcriptional coactivators occupy an important niche in promoting gene transcription in eukaryotes. They lack the sequence-specific DNA-binding activity that characterizes transcriptional activators, but commonly serve two critical functions: (i) as molecular adaptors bridging promoter- and enhancer-bound activators with the transcription machinery and (ii) as agents that serve to overcome the repressive effects of chromatin [1, 2]. In the latter instance, ...
  • OER000002337.pdf.jpg
  • Journal Article

  • The orphan nuclear receptor Nr2f6 impairs skeletal muscle oxidative capacity and regulates muscle mass in mice

    • Authors : malanmy, Nion (2023)

  • The maintenance of skeletal muscle plasticity upon changes in the environment, nutrient supply, and exercise depends on regulatory mechanisms that couple structural and metabolic adaptations. However, the transcriptional control of both processes by nuclear receptors (NR) remains underexplored. Nr2f6 is an orphan NR and a key regulator of metabolism and differentiation. Nonetheless, its role in muscle biology remains elusive. Here, we report,...