Browsing by Subject axit autotaxin

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  • OER000002665.pdf.jpg
  • Journal article


  • Authors : Eymery, Mathias C. (2023)

  • Autotaxin is primarily known for the formation of lysophosphatidic acid (LPA) from 22 lysophosphatidylcholine (LPC). LPA is an important signaling phospholipid that can bind to six 23 G-protein coupled receptors (LPA1-6). The ATX-LPA signaling axis is a critical component in 24 many physiological and pathophysiological conditions. Here, we describe a potent inhibition 25 of Δ9-trans-tetrahydrocannabinol (THC), the main psychoactive compound of medicinal &...