Journal articleAuthors : Tivon, Barr (2021)
Electrophilic peptides that form an irreversible covalent bond with their target have great potential
for binding targets that have been previously considered undruggable. However, the discovery of
such peptides remains a challenge. Here, we present CovPepDock, a computational pipeline for
peptide docking that incorporates covalent binding between the peptide and a receptor cysteine.
We applied CovPepDock retrospectively to a dataset of 115 disulfide-boun... 
