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Journal article

Parallelization with Dual-Trap Single-Column Configuration Maximizes Throughput of Proteomic Analysis

Authors : Kreimer, Simion (2023)

Proteomic analysis on the scale that captures population and biological heterogeneity over hundreds to thousands of samples requires rapid mass spectrometry methods which maximize instrument utilization (IU) and proteome coverage while maintaining precise and reproducible quantification. To achieve this, a short liquid chromatography gradient paired to rapid mass spectrometry data acquisition can be used to reproducibly profile a moderate set of analytes. ...