Journal articleAuthors : Corey, Robin A. (2021)
Integral membrane proteins are localised and/or regulated by lipids present in the surrounding
bilayer. Whilst bacteria such as E. coli have relatively simple membranes when compared to
eukaryotic cells, there is ample evidence that many bacterial proteins bind to specific lipids,
especially the anionic lipid cardiolipin. Here, we apply molecular dynamics simulations to assess
lipid binding to 42 different E. coli inner membrane proteins. O...