Journal articleAuthors : Harder, Oliver F. (2023)
Observing proteins as they perform their tasks has largely remained elusive, which has left our
understanding of protein function fundamentally incomplete. To enable such observations, we have
recently proposed a novel technique that improves the time resolution of cryo-electron microscopy
(cryo EM) to microseconds. Here, we demonstrate that microsecond time-resolved cryo-EM enables
observations of fast protein dynamics. We use our approach to elucidate...