Journal ArticleAuthors : Orsburn, Benjamin C. (2023)
A recent study demonstrated a substantial signal increase when employing a 0.5% acetic acid buffer
additive instead of the traditional 0.1% formic acid used in shotgun proteomics. In this study I compare
these two buffers for a dilution series of tryptic digests down to 20 picograms peptide on column on a
TIMSTOF single cell proteome (SCP) system. I observe a comparable relative level of signal increase as
previously reported... 
