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  • OER000002624.pdf.jpg
  • Journal article

  • A metal ion-dependent mechanism of RAD51 nucleoprotein filament disassembly

    • Authors : Appleby, Robert (2023)

  • The RAD51 ATPase polymerises on single-stranded DNA to form nucleoprotein filaments (NPFs) that are critical intermediates in the DNA strand-exchange reactions of Homologous Recombination (HR). ATP binding is important to maintain the NPF in a competent conformation for strand pairing and exchange. Once strand exchange is completed, ATP hydrolysis licenses the filament for disassembly. Here we show using high-resolution cryoEM that the ATP-binding&#...
  • OER000001959-1.pdf.jpg
  • Ebooks (Sách điện tử)

  • Nanofiltration

    • Authors : Farrukh, Muhammad Akhyar (2018)

  • The nanofiltration technique lies between ultrafiltration and reverse osmosis techniques, and it is considered a low-cost process and is capable of removing pesticides, organic matter, desalination of sea water, oil process and pollutants from industrial wastewater. However, the main challenge in implementation of nanofiltration membrane is its ability towards fouling and low performance at high temperature. The use of nanoparticles in the manufacturing of membranes&#x...