Journal articleAuthors : Rehman, Syed Arif Abdul (2023)
E2 conjugating enzymes (E2s) play a central role in the enzymatic cascade that leads to the 20 attachment of ubiquitin to a substrate. This process, termed ubiquitylation is fundamental for 21 maintaining cellular homeostasis and impacts almost all cellular process. By interacting with 22 multiple E3 ligases, E2s direct the ubiquitylation landscape within the cell. Since its discovery, 23 ubiquitylation has been regarded as a post-translational modification&#... 
