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Journal Article

Xrn1 biochemically associates to the eisosome after the post diauxic shift in yeast

Authors : Courtin, Baptiste (2023)

Gene expression is a crucial and well-orchestrated interplay between transcription, translation, and mRNAs and proteins decay. In eukaryotes, cytoplasmic mRNA decay is intimately linked to translation and mediated for a large part by the 5’- 3’ mRNA degradation pathway. After mRNA decapping by the DCP complex, with the assistance of its co-factors, the mRNA is degraded by the exonuclease Xrn1 (Parker 2012; Fromont-Racine and Saveanu 2014;&#...