Browse

Author Profile

Browsing by Subject mô tả đặc tính

Jump to: 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
or enter first few letters:  
Showing results 1 to 3 of 3
  • OER000002599.pdf.jpg
  • Journal article

  • Discovery and characterization of non-canonical E2 conjugating enzymes

    • Authors : Rehman, Syed Arif Abdul  (2023)

  • E2 conjugating enzymes (E2s) play a central role in the enzymatic cascade that leads to the 20 attachment of ubiquitin to a substrate. This process, termed ubiquitylation is fundamental for 21 maintaining cellular homeostasis and impacts almost all cellular process. By interacting with 22 multiple E3 ligases, E2s direct the ubiquitylation landscape within the cell. Since its discovery, 23 ubiquitylation has been regarded as a post-translational modification&#...
  • OER000003033.pdf.jpg
  • Journal article

  • Identification and characterization of novel plasma proteins in drug resistant HIV/AIDS patients by SWATH-MS

    • Authors : Barik, Sushanta Kumar (2021)

  • Acquired immunodeficiency syndrome is one of the most important diseases caused by human immunodeficiency virus. Understanding its molecular pathogenesis is essential to manage the disease at the population level. In this study, a quantitative analysis of plasma proteins was carried out in drug resistant and drug respondent patients using the SWATH-MS. Sequential window acquisition of all theoretical mass spectra (SWATH-MS) is a prime technique to seek...
  • OER000002772.pdf.jpg
  • Journal article

  • Sensitive detection and structural characterisation of UV-induced cross-links in protein-RNA complexes using CLIR-MS

    • Authors : Sarnowski, Chris P. (2023)

  • Cross-linking coupled with mass spectrometry is an increasingly popular methodology for elucidating structural information from biological complexes. Whilst protein-protein cross-linking workflows are widely used and well characterised, adoption of protein-RNA cross-linking workflows for structural studies is less widespread, and data produced from such experiments remains less well understood. The cross-linking of stable isotope labelled RNA coupled to mass spectrometry (CLIR-MS) workflo...