Journal ArticleAuthors : Scheepers, Ronél (2023)
Although cholesterol is essential for cellular viability and proliferation, it is highly toxic in excess.
The concentration of cellular cholesterol must therefore be maintained within tight tolerances, and
is thought to be subject to a stringent form of homeostasis known as Robust Perfect Adaptation
(RPA). While much is known about the cellular signalling interactions involved in cholesterol
regulation, the specific chemical reaction network structur...