Journal ArticleAuthors : Enustun, Eray (2023)
In the arms race between bacteria and bacteriophages (phages), some large-genome jumbo
phages have evolved a protein shell that encloses their replicating genome to protect it
against DNA-targeting immune factors. By segregating the genome from the host cytoplasm,
however, the “phage nucleus” introduces the need to specifically transport mRNA and
proteins through the nuclear shell, and to dock capsids on the shell for genome packaging.
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