Browse

Author Profile

Browsing by Subject nhiễm sắc thể

Jump to: 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
or enter first few letters:  
Showing results 1 to 4 of 4
  • OER000002305.pdf.jpg
  • Journal Article

  • Genome-scale chromatin interaction dynamic measurements for key components of the RNA Pol II general transcription machinery

    • Authors : Kupkova, Kristyna (2023)

  • Transcription is a highly complex biochemical process whose exquisite regulation is of fundamental importance in determining cell function and fate. A tremendous amount of information is available on the structure, biochemical functions, and relationships of various transcription factors (TFs), co-factors, and subunits of the general transcription machinery (1–5). This includes structures of the transcription preinitiation complex (PIC), which assembl...
  • OER000002508.pdf.jpg
  • Journal article

  • Intracellular biotransformation and disposal mechanisms of magnetosomes in macrophages and cancer cells

    • Authors :  Gandarias, L. (2023)

  • Given their potential clinical applications for the diagnosis and treatment of cancer, it is essential to understand what becomes of them once they are within the body. With this aim, here we have followed the intracellular long-term fate of magnetosomes in two cell types: cancer cells (A549 cell line), because they are the actual target for the therapeutic activity of the magnetosomes, and macrophages (RAW 264.7 cell line), ...
  • OER000002720.pdf.jpg
  • Journal article

  • Rdh54 stabilizes Rad51 at displacement loop intermediates to regulate genetic exchange between chromosomes

    • Authors : Keymakh, Margaret (2023)

  • Homologous recombination (HR) is a double-strand break DNA repair pathway that preserves chromosome structure. To repair the damaged recipient DNA, HR requires an intact donor DNA sequence located elsewhere in the genome. After the double-strand break is repaired, DNA sequence information can be transferred between donor and recipient DNA molecules through different mechanisms, including DNA crossovers that form between homologous chromosomes. Regulating...
  • OER000002309.pdf.jpg
  • Journal Article

  • Structural Basis for the Phase Separation of the Chromosome Passenger Complex

    • Authors : Bryan, Nikaela W. (2023)

  • Membraneless intracellular compartmentalization is central to a long and growing list of biochemical transactions at diverse sub-cellular locations 1. Proteins are by-and-large the drivers of the formation of these compartments, but there is debate about whether their underpinnings are either low-affinity/low-specificity interactions yielding phase separation 2 or multivalent site-specific interactions 3. By its very nature, ascertaining the former type of &#x...