Digital resources - Ha Noi university of science and technology

Browsing by Subject oxy hóa

Jump to: 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
or enter first few letters:

Showing results 1 to 9 of 9

Journal article

A conformational-dependent interdomain redox relay at the core of Protein Disulfide Isomerase activity

Authors : Melo, Eduardo P. (2023)

Protein disulfide isomerases (PDIs) are a family of molecular chaperones resident in the endoplasmic reticulum (ER) emerging as important factors in disease. In addition to an holdase function, some members catalyse disulfide bond formation and isomerization, a crucial step for native folding and prevention of aggregation of misfolded proteins. PDIs are characterized by a modular arrangement of thioredoxin-like domains, with the canonical, first identified PDIA1, ...

Ebooks (Sách điện tử)

Advanced Oxidation Processes - Applications, Trends, and Prospects

Authors : Lecompte, Ciro Bustillo (2020)

Advanced Oxidation Processes - Applications, Trends, and Prospects constitutes a comprehensive resource for civil, chemical, and environmental engineers researching in the field of water and wastewater treatment. The book covers the fundamentals, applications, and future work in Advanced Oxidation Processes (AOPs) as an attractive alternative and a complementary treatment option to conventional methods. This book also presents state-of-the-art research on AOPs and heterogeneous&...

Journal Article

Chemobiosis reveals tardigrade tun formation is dependent on reversible cysteine oxidation

Authors : Smythers, Amanda L. (2023)

Tardigrades, commonly known as ‘waterbears’, are eight-legged microscopic invertebrates renowned for their ability to withstand extreme stressors, including high osmotic pressure, freezing temperatures, and complete desiccation. Limb retraction and expelling their internal water stores results in the tun state, greatly increasing their ability to survive. Emergence from the tun state and/or activity regain follows stress removal, where resumption of life cycle occurs as...

Journal article

Following the fate of lytic polysaccharide monooxygenases (LPMOs) under oxidative conditions by NMR spectroscopy

Authors : Christensen, Idd A. (2023)

Lytic polysaccharide monooxygenases (LPMOs) are copper-dependent enzymes that catalyze oxidative cleavage of polysaccharides, such as cellulose and chitin. LPMO action is key to the efficient varlorization of biomass, but the instability of LPMOs in turnover conditions limits their efficiency. LPMO catalysis requires the presence of a reductant, such as ascorbic acid, and hydrogen peroxide, which can be generated in situ in the presence of molecular oxygen an...

Journal article

Investigating the antioxidant effects of Aloe vera: Possible role in regulating lipid profile and liver function in high fat and fructose diet (HFFD) fed mice

Authors : Abubakar, Abdullahi Mukhtar (2023)

Fat rich diets are believed to induce obesity and contributes to the development of diabetes and 23 cardiovascular disease while high fructose diet was reported to increase gut surface area and 24 enhance nutrient uptake resulting in weight gain. The study investigate the role of Aloe vera 25 supplementation on lipid profiles, oxidative stress as well as liver and hear histology in high fat 26 and fructose diet fed mice....

Journal Article

Measurement of Oxidative Stress in Huh-7 Cell Line to Determine the Effectiveness of PNPLA3 Targeted Gene Therapy for Mitigation of Lipid and Alcohol Induced Oxidative Stress in the

Authors : Kwon, Jihoon (2023)

NAFLD is a condition of increased buildup of fat in the liver, causing lipotoxicity that can manifest to cirrhosis, steatosis and fibrosis, which can cause significant and eventually irreversible damage to the liver. A key gene associated is the PNPLA3 I148M variant, which has been shown to display lipogenesis functionality. However, the role of PNPLA3 in increased ROS formation is debated. Moreover, there are no studies determining&#x...

Journal article

Mechanistic basis for oxidative stress protection of the human tRNA ligase complex by the oxidoreductase PYROXD1

Authors : Loeff, Luuk (2023)

RTCB is the catalytic subunit of the metazoan tRNA ligase complex (tRNA-LC) that plays essential roles in tRNA biogenesis and unfolded protein response. The catalytic center of RTCB contains a conserved cysteine that is susceptible to metal ion-induced oxidative inactivation. The flavin-containing oxidoreductase PYROXD1 preserves the activity of mammalian tRNA-LC in a NAD(P)H-dependent manner, but its protective mechanism remains elusive. Here we report a cryo-EM ...

Journal Article

The orphan nuclear receptor Nr2f6 impairs skeletal muscle oxidative capacity and regulates muscle mass in mice

Authors : malanmy, Nion (2023)

The maintenance of skeletal muscle plasticity upon changes in the environment, nutrient supply, and exercise depends on regulatory mechanisms that couple structural and metabolic adaptations. However, the transcriptional control of both processes by nuclear receptors (NR) remains underexplored. Nr2f6 is an orphan NR and a key regulator of metabolism and differentiation. Nonetheless, its role in muscle biology remains elusive. Here, we report,...

Journal article

β-Carotene oxidation products - function and safety

Authors : Dixit, Vaibhav A. (2021)

β-Carotene oxidation products have newly discovered bioactivity in plants and animals. Synthetic fully oxidized β-carotene (OxBC) has application in supporting livestock health, with potential human applications. The safety of synthetic OxBC has been evaluated. An Ames test showed weak-to-moderate mutagenicity in only one cell line at high concentrations. A mouse micronucleus assay established a non-toxic dose of 1800 mg/kg body weight, and no bone marrow mic...